We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
Read More
8
Vitamin C may help prevent stroke
Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study.
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Read More
9
Vitamin C may lower blood pressure
Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Read More
Most Useful Reviews
7.5
Preventing illness
7 people found this helpful
Fantastic product! Our family has benefited immensely from this over the years. My young son has type 1 diabetes, and it's frightening when he gets sick. We take large doses of vitamin C at the first sign of illness and rarely see any sickness in our home now, even with our two little ones. It's made in the USA and is non-GMO. We mix it with a stevia-based water enhancer that the kids enjoy, as it tastes like juice. I hope this helps others looking for an excellent product.
Read More
6
Improving cardiovascular disease
6 people found this helpful
Really great quality! I recommend this type of vitamin C as it’s more bioavailable. It has fantastic health benefits, reducing blood sugar, improving the cardiovascular system, and acting as an antioxidant. I take a quarter scoop after training; physical exercise boosts vitamin C absorption, making bones stronger. I'll buy more as this one is nearly finished!
Read More
7.5
Gums healing
5 people found this helpful
It’s unfortunate that dentists don’t recommend higher vitamin C doses for periodontal disease! After about a month of taking it, my gums stopped bleeding, which was a relief. If I lower the dosage, the bleeding returns, so I connect this directly to the vitamin C. While the dosage may cause some gastrointestinal discomfort, I prefer that over bleeding and infected gums!
Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Read More
8
Antioxidants show promise for FGR
The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review.
This systematic review focused on the potential effects of antioxidants, particularly vitamin C, on cardiovascular health in cases of fetal growth restriction (FGR). We assessed various studies that examined how these treatments might enhance cardiac and vascular outcomes in affected individuals.
Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.
However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.
Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
Read More
8
Vitamin C may help prevent stroke
Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study.
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Read More
7
Vitamin C enhances NK cell proliferation
Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients.
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.2
All Reviews
Positive Reviews
Negative Reviews
7.5
Preventing illness
7 people found this helpful
Fantastic product! Our family has benefited immensely from this over the years. My young son has type 1 diabetes, and it's frightening when he gets sick. We take large doses of vitamin C at the first sign of illness and rarely see any sickness in our home now, even with our two little ones. It's made in the USA and is non-GMO. We mix it with a stevia-based water enhancer that the kids enjoy, as it tastes like juice. I hope this helps others looking for an excellent product.
Read More
6
Improving cardiovascular disease
6 people found this helpful
Really great quality! I recommend this type of vitamin C as it’s more bioavailable. It has fantastic health benefits, reducing blood sugar, improving the cardiovascular system, and acting as an antioxidant. I take a quarter scoop after training; physical exercise boosts vitamin C absorption, making bones stronger. I'll buy more as this one is nearly finished!
Read More
7.5
Gums healing
5 people found this helpful
It’s unfortunate that dentists don’t recommend higher vitamin C doses for periodontal disease! After about a month of taking it, my gums stopped bleeding, which was a relief. If I lower the dosage, the bleeding returns, so I connect this directly to the vitamin C. While the dosage may cause some gastrointestinal discomfort, I prefer that over bleeding and infected gums!
Read More
Frequently Asked Questions
Cardiovascular disease (CVD) is a broad term that encompasses a range of heart and blood vessel disorders. This can include conditions such as coronary artery disease, which leads to heart attacks; cerebrovascular disease that results in strokes; and peripheral artery disease affecting blood flow to the limbs. The key risk factors for CVD often include high blood pressure, high cholesterol, obesity, smoking, a sedentary lifestyle, and diabetes. By identifying and managing these risk factors, individuals can significantly reduce their likelihood of developing cardiovascular problems.
Prevention and treatment strategies often involve lifestyle modifications such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, alongside engaging in regular physical activity. In some cases, medications might be necessary to control blood pressure or cholesterol levels. Regular check-ups with a healthcare provider are essential for monitoring heart health, especially for individuals with a family history of CVD. Understanding the signs and symptoms of cardiovascular issues—like chest pain, shortness of breath, or fatigue—can help in seeking timely medical attention, ultimately leading to better outcomes.
Ascorbic acid, commonly known as vitamin C, is a water-soluble vitamin that is essential for various bodily functions, including the synthesis of collagen, the absorption of iron, and the maintenance of a healthy immune system. Found naturally in a variety of fruits and vegetables, especially citrus fruits, strawberries, kiwi, and bell peppers, it serves as a potent antioxidant, helping to protect cells from damage by free radicals. Given that the human body cannot synthesize ascorbic acid on its own, it must be obtained through diet or supplementation.
In addition to its fundamental role in supporting overall health, ascorbic acid has garnered interest for its potential benefits in skincare and wound healing. Topical applications of vitamin C can help reduce the appearance of fine lines and improve skin texture, making it a popular ingredient in various cosmetic formulations. Additionally, it plays a crucial role in the body's ability to repair tissues and produce important neurotransmitters. For those looking to boost their vitamin C intake, incorporating a variety of vitamin C-rich foods into your diet or considering a supplement can be effective strategies.
Ascorbic acid, commonly known as vitamin C, has garnered attention for its potential role in cardiovascular health. Several studies suggest that adequate vitamin C intake may contribute to reducing the risk factors associated with cardiovascular disease, such as hypertension and high cholesterol levels. Research indicates that vitamin C can improve endothelial function, which plays a crucial role in maintaining vascular health. Furthermore, its antioxidant properties may help protect the heart by reducing oxidative stress, a contributor to the development of heart disease.
However, while vitamin C can support cardiovascular health, it should not be viewed as a standalone treatment or a substitute for conventional therapies. A balanced diet rich in fruits and vegetables, where vitamin C is abundant, alongside regular exercise and lifestyle modifications, forms the foundation for heart health. Consult with a healthcare professional before making significant changes to your health regimen, particularly if you have existing cardiovascular concerns.
Based on user reviews, those looking to address cardiovascular health with vitamin C may start to notice changes within a month of consistent use. One user highlighted that after a month of taking higher doses, they experienced significant improvements, which they attributed directly to the vitamin C intake Read Review. Users also point to the overall health benefits of vitamin C in improving cardiovascular function and acting as an antioxidant, suggesting that long-term commitment to supplementation might lead to sustained health improvements Read Review.
However, it’s important to note that individual responses can vary based on personal health conditions and lifestyle, such as diet and exercise. While some users might report feeling better or seeing positive changes in their cardiovascular health quickly, others might take longer to experience noticeable results. Therefore, patience and consistent use are recommended for the best outcomes.
Based on the scientific research available, vitamin C shows promise as a supplement for cardiovascular disease, although the extent of its effectiveness and certain mechanisms require further investigation. Several studies highlight its potential in various contexts related to heart health. For instance, a systematic review found that antioxidants, including vitamin C, may enhance cardiac and vascular outcomes, particularly in cases of fetal growth restriction, where they appear to offer some cardiovascular protection [1]. Another study indicates that vitamin C can significantly boost natural killer (NK) cell activity in patients with coronary artery disease, suggesting a potential role in enhancing the immune response in heart conditions [2].
Moreover, vitamin C has been linked to a reduced risk of stroke, particularly cardioembolic stroke, as indicated by a robust Mendelian randomization study showing a noteworthy odds ratio suggesting protective benefits [3]. Additionally, a trial exploring the effects of vitamin C in combination with hawthorn demonstrated significant reductions in blood pressure among workers exposed to heat, providing evidence that it could help manage cardiovascular health in stressful conditions [4]. While these findings are encouraging, they underline the need for more comprehensive research to clarify the direct effects of vitamin C and establish more definitive recommendations for its use in cardiovascular health.
Based on user reviews, many individuals report significant improvements in their health when using vitamin C. One family noted a marked decrease in sickness among their children, particularly in a household with a child who has type 1 diabetes, attributing their success to taking large doses of vitamin C at the onset of illness Read Review. This anecdote highlights vitamin C’s potential role in bolstering immune responses and overall wellness.
Another user experienced specific benefits related to dental health, reporting that their bleeding gums ceased after a month of consistent high-dose vitamin C intake. They noted that any reduction in dosage led to a return of symptoms, which they correlated with the vitamin C supplementation Read Review. This suggests that for some, vitamin C can yield noticeable improvements in conditions like periodontal disease, though individual responses can vary widely based on health status and lifestyle. For the best results, a consistent approach to supplementation may be key.
Users have reported varying experiences when combining this particular vitamin C supplement with other health-related practices, particularly in relation to cardiovascular disease and overall well-being. For instance, one user mentioned their improved cardiovascular system and reduced blood sugar levels, emphasizing that physical exercise enhances vitamin C absorption, which they incorporate into their routine post-training with a quarter scoop of the supplement Read Review. This suggests that users may find synergistic benefits from pairing vitamin C with exercise, potentially amplifying its health effects.
Moreover, another user highlighted a method of administering vitamin C mixed with a stevia-based water enhancer, making it more palatable, especially for kids Read Review. This indicates that users are creative in their approaches to integrating vitamin C into their families’ diets, which may enhance adherence to supplementation. As such, there appears to be a collective acknowledgment of vitamin C's role in supporting cardiovascular health, particularly when combined with other healthy lifestyle choices. However, individual experiences can vary widely, so users should monitor their personal health responses.
Users report varied experiences with dosing Ascorbic Acid for treating cardiovascular disease, emphasizing the importance of finding the right amount. One user noted they take a quarter scoop of this vitamin C supplement after training, highlighting its role in improving cardiovascular health and reducing blood sugar levels (Read Review). Another user found that a higher dose effectively stopped their gum bleeding related to periodontal disease, indicating that a sufficient dose is essential for positive health outcomes, despite some gastrointestinal discomfort (Read Review).
Overall, users suggest that larger doses may offer significant benefits, particularly when it comes to cardiovascular health and alleviating symptoms of related conditions. However, they also caution that individuals may experience side effects at higher doses, necessitating a careful approach to determine the right amount tailored to personal health needs.
7.5
Gums healing
5 people found this helpful
It’s unfortunate that dentists don’t recommend higher vitamin C doses for periodontal disease! After about a month of taking it, my gums stopped bleeding, which was a relief. If I lower the dosage, the bleeding returns, so I connect this directly to the vitamin C. While the dosage may cause some gastrointestinal discomfort, I prefer that over bleeding and infected gums!
6
Improving cardiovascular disease
6 people found this helpful
Really great quality! I recommend this type of vitamin C as it’s more bioavailable. It has fantastic health benefits, reducing blood sugar, improving the cardiovascular system, and acting as an antioxidant. I take a quarter scoop after training; physical exercise boosts vitamin C absorption, making bones stronger. I'll buy more as this one is nearly finished!
7.5
Preventing illness
7 people found this helpful
Fantastic product! Our family has benefited immensely from this over the years. My young son has type 1 diabetes, and it's frightening when he gets sick. We take large doses of vitamin C at the first sign of illness and rarely see any sickness in our home now, even with our two little ones. It's made in the USA and is non-GMO. We mix it with a stevia-based water enhancer that the kids enjoy, as it tastes like juice. I hope this helps others looking for an excellent product.
8
Antioxidants show promise for FGR
The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review.
This systematic review focused on the potential effects of antioxidants, particularly vitamin C, on cardiovascular health in cases of fetal growth restriction (FGR). We assessed various studies that examined how these treatments might enhance cardiac and vascular outcomes in affected individuals.
Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.
However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.
Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
7
Vitamin C enhances NK cell proliferation
Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients.
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
8
Vitamin C may help prevent stroke
Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study.
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
9
Vitamin C may lower blood pressure
Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
References
Rock CR, Miller SL, Allison BJ. The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review. Antioxidants (Basel). 2024;13. 10.3390/antiox13111400
Guo X, Xiao T, Lin L, Gao Q, Lai B, et al. Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients. Front Immunol. 2024;15:1436747. 10.3389/fimmu.2024.1436747
Dong G, Xu W, Xu L. Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study. Nutrients. 2024;16. 10.3390/nu16172818
Du W, Zhang S, Yang J, Fan H. Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial. Asia Pac J Clin Nutr. 2024;33:503. 10.6133/apjcn.202412_33(4).0005